Recent Publications

Articles

• Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
  Sellier C, Campanari ML, Julie Corbier C, Gaucherot A, Kolb-Cheynel I, Oulad-Abdelghani M, Ruffenach F, Page A, Ciura S, Kabashi E, Charlet-Berguerand N : EMBO J, 2016
• Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy.
  Lesage S, Drouet V, Majounie E, Deramecourt V, Jacoupy M, Nicolas A, Cormier-Dequaire F, Hassoun SM, Pujol C, Ciura S, Erpapazoglou Z, Usenko T, Maurage CA, Sahbatou M, Liebau S, Ding J, Bilgic B, Emre M, Erginel-Unaltuna N, Guven G, Tison F, Tranchant C, Vidailhet M, Corvol JC, Krack P, Leutenegger AL, Nalls MA, Hernandez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Singleton A, Corti O, Brice A : Am J Hum Genet, 2016
• The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway.
  Ciura S, Sellier C, Campanari ML, Charlet-Berguerand N, Kabashi E : Autophagy, 2016
• ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress.
  Zaelzer C, Hua P, Prager-Khoutorsky M, Ciura S, Voisin DL, Liedtke W, Bourque CW : Cell Rep, 2015
• Two novel COLVI long chains in zebrafish that are essential for muscle development.
  Ramanoudjame L, Rocancourt C, Lainé J, Klein A, Joassard L, Gartioux C, Fleury M, Lyphout L, Kabashi E, Ciura S, Cousin X, Allamand V : Hum Mol Genet, 2015
• Defining the genetic connection linking amyotrophic lateral sclerosis (ALS) with frontotemporal dementia (FTD).
  Lattante S, Ciura S, Rouleau GA, Kabashi E : Trends Genet, 2015
• Sqstm1 knock-down causes a locomotor phenotype ameliorated by rapamycin in a zebrafish model of ALS/FTLD.
  Lattante S, de Calbiac H, Le Ber I, Brice A, Ciura S, Kabashi E : Hum Mol Genet, 2014
• TREM2 mutations are rare in a French cohort of patients with frontotemporal dementia.
  Lattante S, Le Ber I, Camuzat A, Dayan S, Godard C, Van Bortel I, De Septenville A, Ciura S, Brice A, Kabashi E : Neurobiol Aging, 2013
• Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis.
  Ciura S, Lattante S, Le Ber I, Latouche M, Tostivint H, Brice A, Kabashi E : Ann Neurol, 2013
• Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.
  Vaccaro A, Patten SA, Ciura S, Maios C, Therrien M, Drapeau P, Kabashi E, Parker JA : PLoS One, 2012
• Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4.
  Ciura S, Liedtke W, Bourque CW : J Neurosci, 2011
• Osmotic and thermal control of magnocellular neurosecretory neurons--role of an N-terminal variant of trpv1.
  Sudbury JR, Ciura S, Sharif-Naeini R, Bourque CW : Eur J Neurosci, 2010
• Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse.
  Schorscher-Petcu A, Sotocinal S, Ciura S, Dupré A, Ritchie J, Sorge RE, Crawley JN, Hu SB, Nishimori K, Young LJ, Tribollet E, Quirion R, Mogil JS : J Neurosci, 2010
• Neurophysiology of supraoptic neurons in C57/BL mice studied in three acute in vitro preparations.
  Sharif-Naeini R, Ciura S, Stachniak TJ, Trudel E, Bourque CW : Prog Brain Res, 2008
• TRPV1 gene required for thermosensory transduction and anticipatory secretion from vasopressin neurons during hyperthermia.
  Sharif-Naeini R, Ciura S, Bourque CW : Neuron, 2008
• Contribution of TRPV channels to osmosensory transduction, thirst, and vasopressin release.
  Sharif-Naeini R, Ciura S, Zhang Z, Bourque CW : Kidney Int, 2008
• Neurophysiological characterization of mammalian osmosensitive neurones.
  Bourque CW, Ciura S, Trudel E, Stachniak TJ, Sharif-Naeini R : Exp Physiol, 2007
• [TRPVs: ion channels that make you thirsty!].
  Sharif Naeini R, Ciura S, Bourque CW : Med Sci (Paris), 2006
• Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms.
  Jhas S, Ciura S, Belanger-Jasmin S, Dong Z, Llamosas E, Theriault FM, Joachim K, Tang Y, Liu L, Liu J, Stifani S : J Neurosci, 2006
• Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality.
  Ciura S, Bourque CW : J Neurosci, 2006
• Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension.
  Zaidi SH, You XM, Ciura S, Husain M, Rabinovitch M : Circulation, 2002
• Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice.
  Zaidi SH, You XM, Ciura S, O\\’Blenes S, Husain M, Rabinovitch M : J Clin Invest, 2000