Recent Publications

Articles

• Neu­ro­mus­cu­lar Junc­tion Impair­ment in Amy­otroph­ic Lat­er­al Scle­ro­sis: Reassess­ing the Role of Acetyl­cholinesterase.
  Cam­pa­nari ML, Gar­cía-Ayl­lón MS, Ciu­ra S, Sáez-Valero J, Kabashi E : Front Mol Neu­rosci, 2016
• Loss of C9ORF72 impairs autophagy and syn­er­gizes with polyQ Atax­in-2 to induce motor neu­ron dys­func­tion and cell death.
  Sel­l­i­er C, Cam­pa­nari ML, Julie Cor­bier C, Gaucherot A, Kolb-Cheynel I, Oulad-Abdel­ghani M, Ruf­fe­nach F, Page A, Ciu­ra S, Kabashi E, Charlet-Berguerand N : EMBO J, 2016
• Loss of VPS13C Func­tion in Auto­so­mal-Reces­sive Parkin­son­ism Caus­es Mito­chon­dr­i­al Dys­func­tion and Increas­es PINK1/­Parkin-Depen­dent Mitophagy.
  Lesage S, Drou­et V, Majounie E, Der­ame­court V, Jacoupy M, Nico­las A, Cormi­er-Dequaire F, Has­soun SM, Pujol C, Ciu­ra S, Erpa­pa­zoglou Z, Usenko T, Maurage CA, Sah­ba­tou M, Liebau S, Ding J, Bil­gic B, Emre M, Erginel-Unal­tuna N, Guven G, Tison F, Tran­chant C, Vidail­het M, Cor­vol JC, Krack P, Leuteneg­ger AL, Nalls MA, Her­nan­dez DG, Heutink P, Gibbs JR, Hardy J, Wood NW, Gasser T, Durr A, Deleuze JF, Tazir M, Destée A, Lohmann E, Kabashi E, Sin­gle­ton A, Cor­ti O, Brice A : Am J Hum Genet, 2016
• The most preva­lent genet­ic cause of ALS-FTD, C9orf72 syn­er­gizes the tox­i­c­i­ty of ATXN2 inter­me­di­ate polyg­lu­t­a­mine repeats through the autophagy path­way.
  Ciu­ra S, Sel­l­i­er C, Cam­pa­nari ML, Charlet-Berguerand N, Kabashi E : Autophagy, 2016
• ΔN-TRPV1: A Mol­e­c­u­lar Co-detec­tor of Body Tem­per­a­ture and Osmot­ic Stress.
  Zaelz­er C, Hua P, Prager-Khoutorsky M, Ciu­ra S, Voisin DL, Liedtke W, Bourque CW : Cell Rep, 2015
• Two nov­el COLVI long chains in zebrafish that are essen­tial for mus­cle devel­op­ment.
  Ramanoud­jame L, Rocan­court C, Lainé J, Klein A, Joas­sard L, Gar­tioux C, Fleury M, Lyphout L, Kabashi E, Ciu­ra S, Cousin X, Alla­mand V : Hum Mol Genet, 2015
• Defin­ing the genet­ic con­nec­tion link­ing amy­otroph­ic lat­er­al scle­ro­sis (ALS) with fron­totem­po­ral demen­tia (FTD).
  Lat­tante S, Ciu­ra S, Rouleau GA, Kabashi E : Trends Genet, 2015
• Sqstm1 knock-down caus­es a loco­mo­tor phe­no­type ame­lio­rat­ed by rapamycin in a zebrafish mod­el of ALS/FTLD.
  Lat­tante S, de Cal­bi­ac H, Le Ber I, Brice A, Ciu­ra S, Kabashi E : Hum Mol Genet, 2014
• TREM2 muta­tions are rare in a French cohort of patients with fron­totem­po­ral demen­tia.
  Lat­tante S, Le Ber I, Camuzat A, Dayan S, Godard C, Van Bor­tel I, De Septenville A, Ciu­ra S, Brice A, Kabashi E : Neu­ro­bi­ol Aging, 2013
• Loss of func­tion of C9orf72 caus­es motor deficits in a zebrafish mod­el of amy­otroph­ic lat­er­al scle­ro­sis.
  Ciu­ra S, Lat­tante S, Le Ber I, Latouche M, Tostivint H, Brice A, Kabashi E : Ann Neu­rol, 2013
• Meth­yl­ene blue pro­tects against TDP-43 and FUS neu­ronal tox­i­c­i­ty in C. ele­gans and D. rerio.
  Vac­caro A, Pat­ten SA, Ciu­ra S, Maios C, Ther­rien M, Dra­peau P, Kabashi E, Park­er JA : PLoS One, 2012
• Hyper­tonic­i­ty sens­ing in organum vas­cu­lo­sum lam­i­na ter­mi­nalis neu­rons: a mechan­i­cal process involv­ing TRPV1 but not TRPV4.
  Ciu­ra S, Liedtke W, Bourque CW : J Neu­rosci, 2011
• Osmot­ic and ther­mal con­trol of mag­no­cel­lu­lar neu­rose­cre­to­ry neurons–role of an N-ter­mi­nal vari­ant of trpv1.
  Sud­bury JR, Ciu­ra S, Sharif-Naei­ni R, Bourque CW : Eur J Neu­rosci, 2010
• Oxy­tocin-induced anal­ge­sia and scratch­ing are medi­at­ed by the vaso­pressin-1A recep­tor in the mouse.
  Schorsch­er-Petcu A, Sotoci­nal S, Ciu­ra S, Dupré A, Ritchie J, Sorge RE, Craw­ley JN, Hu SB, Nishi­mori K, Young LJ, Tri­bol­let E, Quiri­on R, Mogil JS : J Neu­rosci, 2010
• Neu­ro­phys­i­ol­o­gy of supraop­tic neu­rons in C57/BL mice stud­ied in three acute in vit­ro prepa­ra­tions.
  Sharif-Naei­ni R, Ciu­ra S, Stach­ni­ak TJ, Trudel E, Bourque CW : Prog Brain Res, 2008
• TRPV1 gene required for ther­mosen­so­ry trans­duc­tion and antic­i­pa­to­ry secre­tion from vaso­pressin neu­rons dur­ing hyper­ther­mia.
  Sharif-Naei­ni R, Ciu­ra S, Bourque CW : Neu­ron, 2008
• Con­tri­bu­tion of TRPV chan­nels to osmosen­so­ry trans­duc­tion, thirst, and vaso­pressin release.
  Sharif-Naei­ni R, Ciu­ra S, Zhang Z, Bourque CW : Kid­ney Int, 2008
• Neu­ro­phys­i­o­log­i­cal char­ac­ter­i­za­tion of mam­malian osmosen­si­tive neu­rones.
  Bourque CW, Ciu­ra S, Trudel E, Stach­ni­ak TJ, Sharif-Naei­ni R : Exp Phys­i­ol, 2007
• [TRPVs: ion chan­nels that make you thirsty!].
  Sharif Naei­ni R, Ciu­ra S, Bourque CW : Med Sci (Paris), 2006
• Hes6 inhibits astro­cyte dif­fer­en­ti­a­tion and pro­motes neu­ro­ge­n­e­sis through dif­fer­ent mech­a­nisms.
  Jhas S, Ciu­ra S, Belanger-Jas­min S, Dong Z, Llam­osas E, The­ri­ault FM, Joachim K, Tang Y, Liu L, Liu J, Sti­fani S : J Neu­rosci, 2006
• Tran­sient recep­tor poten­tial vanil­loid 1 is required for intrin­sic osmore­cep­tion in organum vas­cu­lo­sum lam­i­na ter­mi­nalis neu­rons and for nor­mal thirst respons­es to sys­temic hyper­os­mo­lal­i­ty.
  Ciu­ra S, Bourque CW : J Neu­rosci, 2006
• Over­ex­pres­sion of the ser­ine elas­tase inhibitor elafin pro­tects trans­genic mice from hypox­ic pul­monary hyper­ten­sion.
  Zai­di SH, You XM, Ciu­ra S, Husain M, Rabi­novitch M : Cir­cu­la­tion, 2002
• Sup­pressed smooth mus­cle pro­lif­er­a­tion and inflam­ma­to­ry cell inva­sion after arte­r­i­al injury in elafin-over­ex­press­ing mice.
  Zai­di SH, You XM, Ciu­ra S, O\\’Blenes S, Husain M, Rabi­novitch M : J Clin Invest, 2000