Recent Publications

Articles

• Decer­e­brate mouse mod­el for stud­ies of the spinal cord cir­cuits.
  Mee­han CF, Mayr KA, Manuel M, Nakan­ishi ST, Whe­lan PJ : Nat Pro­toc, 2017
• MuSK friz­zled-like domain is crit­i­cal for mam­malian neu­ro­mus­cu­lar junc­tion for­ma­tion and main­te­nance.
  Messéant J, Dob­bertin A, Girard E, Del­ers P, Manuel M, Man­gione F, Schmitt A, Le Den­mat D, Mol­gó J, Zyt­nic­ki D, Scha­ef­fer L, Legay C, Strochlic L : J Neu­rosci, 2015
• Adult spinal motoneu­rones are not hyper­ex­citable in a mouse mod­el of inher­it­ed amy­otroph­ic lat­er­al scle­ro­sis
  Delestrée N, Manuel M, Igle­sias C, Elba­siouny SM, Heck­man CJ, Zyt­nic­ki D : J Phys­i­ol, 2014
• The den­drit­ic loca­tion of the L-type cur­rent and its deac­ti­va­tion by the somat­ic AHP cur­rent both con­tribute to fir­ing bista­bil­i­ty in motoneu­rons
  Manuel M, Zyt­nic­ki D, Meu­nier C : Front Com­put Neu­rosci, 2014
• Char­ac­ter­i­za­tion of motor units in behav­ing adult mice shows a wide pri­ma­ry range
  Rit­ter LK, Tresch MC, Heck­man CJ, Manuel M, Tys­sel­ing VM : J Neu­ro­phys­i­ol, 2014
• Push-pull con­trol of motor out­put
  John­son MD, Hyn­gstrom AS, Manuel M, Heck­man CJ : J Neu­rosci, 2012
• NMDA induces per­sis­tent inward and out­ward cur­rents that cause rhyth­mic burst­ing in adult rodent motoneu­rons
  Manuel M, Li Y, Elba­siouny SM, Mur­ray K, Griener A, Heck­man CJ, Ben­nett DJ : J Neu­ro­phys­i­ol, 2012
• Simul­ta­ne­ous intra­cel­lu­lar record­ing of a lum­bar motoneu­ron and the force pro­duced by its motor unit in the adult mouse in vivo
  Manuel M, Heck­man CJ : J Vis Exp, 2012
• Stronger is not always bet­ter: could a body­build­ing dietary sup­ple­ment lead to ALS?
  Manuel M, Heck­man CJ : Exp Neu­rol, 2011
• Extra forces evoked dur­ing elec­tri­cal stim­u­la­tion of the mus­cle or its nerve are gen­er­at­ed and mod­u­lat­ed by a length-depen­dent intrin­sic prop­er­ty of mus­cle in humans and cats
  Frigon A, Thomp­son CK, John­son MD, Manuel M, Horn­by TG, Heck­man CJ : J Neu­rosci, 2011
• Mixed mode oscil­la­tions in mouse spinal motoneu­rons arise from a low excitabil­i­ty state
  Igle­sias C, Meu­nier C, Manuel M, Tim­o­fee­va Y, Delestrée N, Zyt­nic­ki D : J Neu­rosci, 2011
• Alpha, beta and gam­ma motoneu­rons: func­tion­al diver­si­ty in the motor system’s final path­way
  Manuel M, Zyt­nic­ki D : J Inte­gr Neu­rosci, 2011
• Adult mouse motor units devel­op almost all of their force in the sub­pri­ma­ry range: a new all-or-none strat­e­gy for force recruit­ment?
  Manuel M, Heck­man CJ : J Neu­rosci, 2011
• Fast kinet­ics, high-fre­quen­cy oscil­la­tions, and sub­pri­ma­ry fir­ing range in adult mouse spinal motoneu­rons.
  Manuel M, Igle­sias C, Don­net M, Leroy F, Heck­man CJ, Zyt­nic­ki D : J Neu­rosci, 2009
• Res­o­nant or not, two ampli­fi­ca­tion modes of pro­pri­o­cep­tive inputs by per­sis­tent inward cur­rents in spinal motoneu­rons.
  Manuel M, Meu­nier C, Don­net M, Zyt­nic­ki D : J Neu­rosci, 2007
• The after­hy­per­po­lar­iza­tion con­duc­tance exerts the same con­trol over the gain and vari­abil­i­ty of motoneu­rone fir­ing in anaes­thetized cats.
  Manuel M, Meu­nier C, Don­net M, Zyt­nic­ki D : J Phys­i­ol, 2006
• How much after­hy­per­po­lar­iza­tion con­duc­tance is recruit­ed by an action poten­tial? A dynam­ic-clamp study in cat lum­bar motoneu­rons.
  Manuel M, Meu­nier C, Don­net M, Zyt­nic­ki D : J Neu­rosci, 2005